Question
By way of your final answer.
That is my time that is second I this concern.
I have re-done an intensive research about the structure of male genitalia. Simply speaking, as it happens that information out there was inconsistent. In Wikipedia, two split entries of Foreskin’ and Mucous membrane’ yield contradictory outcomes: the previous states the glans penis (head associated with the penis) and glans clitoridis and also the within the prepuce (foreskin) and hood that is clitoral perhaps maybe not mucous membranes’, even though the latter says that the internal foreskin is just a mucous membrane just like the within the eyelid or perhaps the lips. ‘ in addition, in accordance with glans penis’ of wikipedia, The epithelium regarding the glans penis is mucocutaneous tissue.’
By the means we learned that the foreskin consists of Langerhans cells that are recognized as receptor of HIV virus (these details arises from OU Handbook of GUM and HIV medicine).
I’ve talked about these problems by having a psychiatrist (this is because i’m i am acutely concerned throughout the whole HIV/STD thingy) who warned me personally that i ought ton’t be doing penis-to-penis side-along rubbing and penis docking anymore because `it’s rubbing of mucosal cells. HIV/STD virus is likely to pass between. Why can you simply just take such dangers?’
In your last answer (answer that is final), you stated that the transmission danger of dick-docking is basically nonexistent and implied that penis-to-penis side-along rubbing does maybe maybe not pose any transmission risk as the only mucous membrane associated with the entire cock (including shaft, foreskin, glans penis) could be the liner associated with the urethra through the pee-hole up to your bladder. But i did not point out that i am uncircumcised. There is loads of internal foreskin whose nature that is very extremely dubious of mucous membrane layer and that will be filled with Langerhans cells.
Therefore my questions are: (1) can you please reiterate your viewpoint regarding the transmission chance of dick-docking and penis-to-penis rubbing that is side-along citing the real reason for?? let’s say certainly one of us shot the strain? Would the strain shoot right at the urethra during docking. (2) should we put for a condom although we do dick-docking and penis-to-penis side-along rubbing? (3) must I perform a circumcision, as some studies from Kenya(!) recommend it decreases the possibility of transmission of HIV as well as other STDs? Do you think it?? (4) exactly why are Langerhans cells cited as vunerable to HIV infection? Exactly What part does it play ?? (5) exactly why is the word `mucous membrane layer’ so important in HIV infection? What exactly is it anyway?? Would HIV or any other STDs have over the membrane layer and infect CincinnatiOH escort others??
As bothersome as i will be, we sincerely do hope that you’dn’t find my queries unpleasant or devious at all. Debate contributes to better understanding. In order you painstakingly answer my questions? for me to have some sort of peace, could?
We vow We shall donate USD150 to your charity investment.
Response
My estimation regarding HIV transmission/acquisition associated to frottage (penis-to-penis rubbing, «dick-docking») remains unchanged. It is really not regarded as a danger. Could a load is shot by you and strike the urethra? Yes, it is theoretically feasible, but not very possible, that the spunk would come into significant actually experience of the urethra’s mucous membrane.
If that would make you are feeling safer much less anxious, yes. Really, I do not feel it is necessary.
The studies do indicate that male circumcision decreases the chance for acquiring HIV. But, in the event that you follow safer intimate techniques, I do not feel it really is necessary.
Langerhan’s cells (dendritic cells) perform a essential part in the initiation of HIV disease by virtue associated with cap ability of HIV to bind to certain cellular area receptors of the cells. This enables efficient presentation of HIV to CD4 cells that then become contaminated. The foreskin contains Langerhan’s cells.
A membrane that is mucous a slim layer (membrane layer) that lines all interior human body passages that communicate straight with atmosphere outside of the human anatomy, like the breathing and alimentary tracts, and that has specialized cells or glands that secrete mucous. HIV can permeate mucous membranes, nonetheless it cannot permeate intact epidermis. The foreskin is certainly not a membrane that is mucous. But, it really is a specific kind of epidermis and HIV could be taken on by the Langerhan’s (dendritic) cells situated in the foreskin.
We truly don’t find your inquiries either devious or»offensive.» It could be somewhat confusing to try and explain complex information on physiology or even the purpose of specific cells in a forum similar to this forum. Therefore the physiology class is finished for today.